Vol 4-2 Case Report
Vol 4-2 Review Article

Scientific Evaluation of EMDR Psychotherapy for the Treatment of Psychological Trauma Summary: Scientific evaluation of EMDR psychotherapy

F. Haour1*, E. Dobbelaere1,2, C. de Beaurepaire3

1EMDR France Association, 9 rue Papillon, 75009 Paris, France

2Université Paris 5, 75006 Paris, France

3EPS of Maison-Blanche, 6-10, Pierre-Bayle Street, 75020 Paris, France

DOI: 10.29245/2572.942X/2019/2.1234 View / Download Pdf View Full Text
Vol 4-2 Research Article

Gulf War Illness and Inflammation: Association of symptom severity with C-reactive protein

Lisa M. James1,2,3, Brian E. Engdahl1,2,4, Rachel A. Johnson1, Apostolos P. Georgopoulos1,2,3,4,5*

1Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis, MN, 5541, USA

2Department of Neuroscience, University of Minnesota Medical School, Minneapolis, MN 55455, USA

3Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55455, USA

4Department of Psychology, University of Minnesota Medical School, Minneapolis, MN 55455, USA

5Department of Neurology, University of Minnesota Medical School, Minneapolis, MN 55455, USA

Gulf War Illness (GWI) is a chronic multi-system condition that has affected one-third of U.S. veterans who served in the Persian Gulf. Although GWI etiology remains unclear, mounting evidence points to immune system involvement and inflammation, in particular, as underlying the host of symptoms associated with the condition. Here we investigated the association between GWI symptoms and C-reactive protein (CRP), a marker of inflammation, in 76 veterans with GWI. Results indicated a highly significant positive association between CRP and mean GWI symptom severity. At the symptom domain level, CRP was significantly and positively associated with Pain, Neurocognitive/Mood, Fatigue, and Respiratory symptom severity but not with Skin or Gastrointestinal symptom severity. These results support the premise that GWI symptoms, particularly those implicating brain involvement, are a result of neuroinflammation. The cause for inflammation is not known. We have hypothesized that at the root of GWI are harmful persistent antigens stemming from environmental exposures associated with service during the Gulf War that could not be successfully eliminated due to lack of specific immunity1,2. Work is underway in our laboratory to identify and eliminate persistent antigens in veterans with GWI which we anticipate will result in reduced inflammation and reduced GWI symptoms.

DOI: 10.29245/2572.942X/2019/2.1245 View / Download Pdf View Full Text
Vol 4-2 Commentary

"Commentary: Alcohol Consumption Impairs the Ependymal Cilia Motility in the Brain Ventricles"

Hannah C. Saternos1 and Wissam A. AbouAlaiwi1*

1University of Toledo, College of Pharmacy and Pharmaceutical Sciences, Department of Pharmacology and Experimental Therapeutics, Toledo, Ohio, USA

DOI: 10.29245/2572.942X/2019/2.1250 View / Download Pdf View Full Text