Vol 8-3 Commentary

Commentary: T1 Mapping from routine 3D T1-weighted inversion recovery sequences in clinical practice: comparison against reference inversion recovery fast field echo T1 scans and feasibility in multiple sclerosis

Vivian S. Nguyen1*, Griffin J. Young2, Adil Javed1, Timothy J. Carroll2

1Department of Neurology, The University of Chicago, Chicago, IL, USA

2Department of Radiology, The University of Chicago, Chicago, IL, USA

MRI has long been a critical tool for diagnosing and monitoring Multiple Sclerosis (MS). Conventional MRI employed in clinical practice is non-parametric, which disallows quantitative measures of tissue damage. This creates an unmet need to develop a post-acquisition image processing algorithm that can convert a qualitative image into a corresponding quantitative map. We present a methodology that can convert a clinically routine T1-weighted MPRAGE image into a parametric T1 map with high accuracy and precision in relation to a commonly used T1 mapping reference standard. We evaluate the methodology’s performance in Multiple Sclerosis for the purpose of quantifying tissue damage primarily in lesions and secondarily in white matter and gray matter regions.

DOI: 10.29245/2572.942X/2024/3.1305 View / Download Pdf
Vol 8-3 Mini Review

A Brief Review on Clinical Treatment of Oculogyric Crisis

Liping Wu, Tao Lv*

The People’s Hospital of Deyang, North Taishan Road, Deyang, Sichuan, China

As of now, there are increasing cases related to oculogyric crisis (OGC), mainly focusing on clinical manifestations. The pathogenesis of OGC is still uncertain, and there is no unified treatment protocol. This review aims to explore the treatment and management strategies for OGC based on existing cases, hoping to provide references for clinicians in identifying and treating OGC in practice.

DOI: 10.29245/2572.942X/2024/3.1304 View / Download Pdf